September 2023

A New In Vivo Study

In an increasingly connected and hectic world, sleep problems have become a common challenge affecting many people. From difficulty falling asleep to waking up in the middle of the night with a restless mind, sleep disorders can have a significant impact on our quality of life. Lack of adequate sleep can not only leave us feeling tired and sleepy during the day, but can also affect our cognitive, emotional and physical performance.

That’s why it is important to be aware of the critical role that melatonin plays in sleep quality. It is the centre on which our body’s circadian cycles are based, and therefore having optimal levels of this hormone in our body is fundamental to having an adequate quality of sleep.

The latest Affron® Research

The latest in vivo study on affron® and melatonin has yielded extremely promising results in the area of improving sleep and well-being. This study delved into the interaction between affron®, the premium saffron extract, and melatonin, the key hormone regulating our sleep-wake cycle.

In this study, affron® was shown to have the ability to stimulate endogenous melatonin production in the body. Natural melatonin production is essential for maintaining quality sleep and ensuring that we are in tune with our circadian rhythms. Affron® demonstrated its ability to promote the synthesis of enzymes that convert tryptophan to melatonin while inhibiting enzymes that convert tryptophan to kynurenine, a compound that may be associated with stress and other disorders.

These results are exciting as they suggest that affron® may offer a natural and effective way to improve sleep quality by encouraging the body to generate its own melatonin. This has the potential to be a beneficial alternative to solve sleep problems among natural product lovers.