focusOnMens

Functionality in the area of men’s health.

From the Biogredia portfolio, here are some key ingredients worthy of consideration in new and revised formulations.

Plasys300®

from Pharmactive is a unique proprietary combination of cereal pollen standardized to ≥ 50% phytosterols (as β-sitosterol) by GC and ≥ 1% essential amino
acids by HPLC.

β-sitosterol is a phytosterol that has clinical evidence as an inhibitor for testosterone production*.

Essential amino acids from pollen have potent anti-inflammatory properties, as well as clinical evidence for palliating benign prostate hyperplasia symptoms*.

Plasys300® is especially designed for men’s healthy ageing demands. It blocks the over-stimulation
of α-adrenergic receptors at the prostate, reducing the urinary tract vasoconstriction as well as urinary discomfort symptoms*.
Plasys300® offers anti-proliferative effects at the prostatic cells, preventing prostate enlargement*.

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Liboost®

from Pharmactive is a damiana extract (Turnera diffusa) standardized to ≥1.5% bioflavonoids by HPLC and to a pool of 3 biomolecules, which have been related to sexual appetite boost properties*.

Liboost® main mechanisms of action for men:
• Nitric Oxide (NO) release: Liboost® may increase NO release in endothelial tissue, promoting vasodilatation*.

• PDE-5 (phosphodiesterase type 5) activity inhibition: Liboost® may inhibit an enzyme key to the degradation of cGMP, which induces smooth muscle relaxation, resulting in penile erection*.

• Testosterone levels balance: Liboost®, may inhibit testosterone degradation, maintaining its levels for an adequate erectile function*.

Affron®

from Pharmactive is backed by 8 human clinical studies that have shown improved mood in healthy consumers with occasional stress and anxiety, and to improve sleeplessness*.

The following main mechanisms of action of affron® have been identified:
• Inhibition of the reuptake mechanism of dopamine, norepinephrine, and serotonin, increasing the concentrations of these neurotransmitters in the synaptic cleft of neurons, thereby improving mood balance*.

• Antioxidant effect against the excessive oxidative stress produced during occasional anxiety or stress processes in the central nervous system*.

• Anti-inflammatory action in stressed neural tissue, decreasing hippocampal levels of apoptotic biomarkers and stress signal molecules*.

A new, randomized, double-blind, placebo-controlled study provided further confirmation of the sleep-enhancing effects of 28 days of affron® supplementation at 14 mg, 1 hour before bedtime. For the first time, a single dose of affron® 1 hour before sleep revealed the new possible mechanism of action influencing sleep hormones.

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Sensoril®

Ashwagandha from Kerry displays attributes which include lowest clinically substantiated dosing for reducing overall stress/anxiety – patented, and with THREE bioactives.

Sensoril® Ashwagandha is a powerful adaptogen derived from a unique blend of both leaves and roots of the Withania somnifera plant to provide optimal efficacy and bioactive diversity. The proprietary blend has been studied in more than ten human clinical trials. Sensoril® has excellent applications in supplements, foods, beverages, and personal care products.

• Manages and reduces stress
• Boosts energy levels
• Improves focus and reaction time
• Increases upper & lower body strength
• Improves sleep quality
• Improves mental cognitive health, mood, fatigue, and vitality
• Supports joint health
• Supports cardiovascular health
• Supports healthy endothelial function and a healthy lipid profile

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ABG10+®

from Pharmactive is a unique aged black garlic ingredient, standardized to ≥0.1% S-allyl cysteine (SAC) by HPLC. It is a highly stable and bioavailable biomolecule that has been associated in several studies to the inhibition of oxidative damage as a result of its potent antioxidant and cardioprotective properties*.

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The key to obtaining these ABG+® unique features, is to gather them exactly when the concentration of SAC is higher in the bulb*
The following ABG+ ® mechanisms of action have been identified:
• Decreasing coronary perfusion pressure, therefore improving heart contraction*.
• Balancing blood pressure*.
• Helping alleviate oxidative stress*.

Disclaimer
These is a summary of published research but has not been evaluated by the European Food Safety Authority (EFSA) or other pertinent Regulatory Authority. This product
is not intended to diagnose, treat, cure or prevent any disease.

Please get in touch if you want more information or have questions about our ingredients.

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